Medical Research Ethics Committee NedMec

Medical Research Ethics Committee NedMec

The Medical Research Ethics Committee (MREC) NedMec is a recognized medical research ethics committee to which the Antoni van Leeuwenhoek, the Princess Máxima Center for pediatric oncology and the UMC Utrecht are affiliated. This MREC was created after the merger of the MREC Utrecht and the MREC Antoni van Leeuwenhoek on 1-1-2022.

From 12 September 2022, the METC NedMec can be reached by email via and

Through its national scope, the MREC NedMec reviews not only for researchers at its member institutions, but also for various other researchers and (government) institutions in the health care sector.

The committee draws on broad expertise, with experienced members from the various disciplines. It is therefore able to swiftly and effectively review all types of medical research, including the most complex trials. In addition, MREC NedMec has specific expertise and a unique position in the area of reviewing research into (pediatric) oncology, oncological drug research and research involving children.

Number of studies reviewed in 2021:

MREC UtrechtMREC Antoni van LeeuwenhoekTotal
Total number of studies13855193
Studies with medicinal products502777
Studies with medical devices261238

The MREC NedMec has three chambers, each with its own specialty: Medicinal Products (G), Oncology (O) and All-round (A). Each of the three affiliated institutions participates in these chambers with committee members from the various disciplines who have specific expertise in these areas. This ensures the quality and independence of the review. Each chamber meets every other week to keep the review times as short as possible.

On this site you will find information on review according to the Medical Research Involving Human Subjects Act (WMO), submitting a research file to the MREC NedMec and related issues.

Quick acces to uitklapper, klik om te openen

Due to the coronavirus, modified procedures apply.

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Research with medicinal products

Consult the CCMO website for more information on research with medicinal products.

CCMO 'Clinical trials with medicinal products'

Research with medical devices

Consult the CCMO and IGJ websites for more information on research with medical devices.

CCMO 'Clinical investigations with medical devices'
CCMO 'Performance studies using in-vitro diagnostics (IVDR)'
IGJ 'Clinical research with medical devices'

Institutional Policy

For questions and more information about your institution's policy on medical research involving human subjects, please see the pages below: 

Antoni van Leeuwenhoek
Prinses Máxima Center
UMC Utrecht

Participating institutions: UMC Utrecht, Prinses Máxima Center for pediatric oncology and Antoni van Leeuwenhoek

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